
The meek flower shop assistant Seymour (played by Noah Miller) pines for co-worker Audrey (played by Anna Johnson). During a total eclipse of the sun, he discovers an unusual plant he names Audrey II (voiced by Bryce Abeln, Puppeteer Devon Fowler).
The growing plant generates a lot of new business for the struggling store which delights the shop owner, Mr. Mushnik (played by Colin Salewski). The show is full of quirky characters including four street urchins who act as a Greek Chorus through the show (Amanda Simmons, Zoe Schuck, Mayra Sandoval, and Adalie Nelson), a nitrious oxide loving dentist (Evan Ewing), and many more dwellers of Skid Row (Orion Anderson, Kindle Spivey, and Kylee Longaker).